Koo Tsai Kee (Template:Zh) is a Singaporean associate professor and former politician. He was a Member of Parliament from 1991 to 2011, representing the Tiong Bahru division under the Tanjong Pagar Group Representation Constituency (Tanjong Pagar GRC).
Koo was educated in Raffles Institution. He holds a Bachelor of Surveying with first class honours from the universities of Newcastle and New South Wales. He also attended University College London and has a Graduate Diploma in photogrammetry, Master of Science and Master of Philosophy.
Koo has held the position of Parliamentary Secretary in various ministries, including Finance, National Development, Defence, and Environment and Water Resources. Koo was promoted to Minister of State in the Ministry of Defence in May 2006.
Koo retired from politics in April 2011.